Oral pyogenic granuloma: a review
Top Cited Papers
Open Access
- 1 January 2006
- journal article
- review article
- Published by Nihon University School of Dentistry in Journal of Oral Science
- Vol. 48 (4), 167-175
- https://doi.org/10.2334/josnusd.48.167
Abstract
Pyogenic granuloma is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low-grade local irritation, traumatic injury or hormonal factors. It predominantly occurs in the second decade of life in young females, possibly because of the vascular effects of female hormones. Clinically, oral pyogenic granuloma is a smooth or lobulated exophytic lesion manifesting as small, red erythematous papules on a pedunculated or sometimes sessile base, which is usually hemorrhagic. The surface ranges from pink to red to purple, depending on the age of the lesion. Although excisional surgery is the treatment of choice for it, some other treatment protocols such as the use of Nd:YAG laser, flash lamp pulsed dye laser, cryosurgery, intralesional injection of ethanol or corticosteroid and sodium tetradecyl sulfate sclerotherapy have been proposed. Because of the high frequency of pyogenic granuloma in the oral cavity, especially during pregnancy, and necessity for proper diagnosis and treatment, a complete review of published information and investigations about this lesion, in addition to knowledge about new approaches for its treatment is presented. (J. Oral Sci. 48, 167-175, 2006)Keywords
This publication has 44 references indexed in Scilit:
- Pyogenic granuloma of the oral cavity: Comparative study of its clinicopathological and immunohistochemical featuresPathology International, 2005
- Pyogenic granuloma subsequent to injury of a primary tooth. A case reportInternational Journal of Paediatric Dentistry, 2002
- Inducible nitric oxide synthase is expressed in granuloma pyogenicumBritish Journal of Dermatology, 1998
- Pyogenic Granuloma Associated With Guided Tissue Regeneration: A Case ReportThe Journal of Periodontology, 1996
- An Intestinal Counterpart of Pyogenic Granuloma of the SkinThe American Journal of Surgical Pathology, 1995
- Epulides: a clinicopathological study of a series of 200 consecutive lesionsBritish Dental Journal, 1987
- Pyogenic granuloma: Evaluation of oral conditionsBritish Journal of Oral and Maxillofacial Surgery, 1986
- Multiple granulation tissue lesions occurring in isotretinoin treatment of acne vulgaris—successful response to topical corticosteroid therapyJournal of the American Academy of Dermatology, 1985
- Lobular capillary hemangiomaThe American Journal of Surgical Pathology, 1980
- Oral Pyogenic Granuloma as a Complication of Pregnancy and the Use of Hormonal ContraceptivesInternational Journal of Gynecology & Obstetrics, 1976