Size Does Matter: Donor Renal Volume Predicts Recipient Function Following Live Donor Renal Transplantation
- 28 February 2011
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Urology
- Vol. 185 (2), 605-609
- https://doi.org/10.1016/j.juro.2010.09.098
Abstract
With the now routine use of computerized tomography angiography with 3-dimensional reconstruction in the donor evaluation, renal volume can be easily determined using volume calculating software. We evaluated whether donor renal volume could predict recipient renal function. Clinical data of all donor and recipient pairs undergoing live donor kidney transplantation at our institution between January 2006 and October 2009 were reviewed. The volume of the kidney selected for transplant was determined using volume calculating software, and correlated to transplant recipient nadir and 1-year serum creatinine. Multivariate regression analysis was performed to adjust for demographic and clinical variables. During the study period 114 patients underwent live donor renal transplantation. Recipient nadir and 1-year serum creatinine levels were significantly correlated with the volume of donated kidney even after adjusting for age, body mass index, body surface area and donor creatinine clearance. Kidney volume also retained significance after excluding recipients from analysis who experienced acute rejection episodes. Larger kidney volumes calculated using 3-dimensional computerized tomography with volume calculating software are correlated with lower recipient nadir and 1-year serum creatinine levels.Keywords
This publication has 16 references indexed in Scilit:
- Optimizing Living Donor Kidney Graft Function by Donor-Recipient Pair SelectionTransplantation, 2006
- Donor Kidney Volume and Outcomes Following Live Donor Kidney TransplantationAmerican Journal of Transplantation, 2006
- Impact of Graft Mass on the Clinical Outcome of Kidney TransplantsJournal of the American Society of Nephrology, 2005
- Preoperative renal volumes as a predictor of graft function in living donor transplantationAmerican Journal of Kidney Diseases, 2004
- Computerized Tomography With 3-Dimensional Reconstruction for the Evaluation of Renal Size and Arterial Anatomy in the Living Kidney DonorJournal of Urology, 2004
- Effect of Donor/Recipient Body Weight Mismatch on Patient and Graft Outcome in Living-Donor Kidney TransplantationAmerican Journal of Nephrology, 2003
- Post-transplant renal function in the first year predicts long-term kidney transplant survivalKidney International, 2002
- Influence of allograft size to recipient body-weight ratio on the long-term outcome of renal transplantationBritish Journal of Surgery, 2000
- THE EFFECT OF KIDNEY SIZE ON CADAVERIC RENAL ALLOGRAFT OUTCOME1Transplantation, 1996
- IMPACT OF DONOR/RECIPIENT SIZE MATCHING ON OUTCOMES IN RENAL TRANSPLANTATION1Transplantation, 1996