Glycoproteins of coated pits, cell junctions, and the entire cell surface revealed by monoclonal antibodies and immunoelectron microscopy.

Abstract

Topographical descriptions of 3 major plasma membrane glycoproteins of murine 3T3 cells were obtained by immunoelectron microscopy with monoclonal antibodies. A glycoprotein of MW 80,000 was distributed throughout the total cell surface. A second of MW 90,000 was concentrated in coated pits, and a third of MW 100,000 was localized at cell junctions.