Gold Nanoparticles for Photoacoustic Imaging
Top Cited Papers
- 20 January 2015
- journal article
- review article
- Published by Informa UK Limited in Nanomedicine
- Vol. 10 (2), 299-320
- https://doi.org/10.2217/nnm.14.169
Abstract
Photoacoustic (PA) imaging is a biomedical imaging modality that provides functional information regarding the cellular and molecular signatures of tissue by using endogenous and exogenous contrast agents. There has been tremendous effort devoted to the development of PA imaging agents, and gold nanoparticles as exogenous contrast agents have great potential for PA imaging due to their inherent and geometrically induced optical properties. The gold-based nanoparticles that are most commonly employed for PA imaging include spheres, rods, shells, prisms, cages, stars and vesicles. This article provides an overview of the current state of research in utilizing these gold nanomaterials for PA imaging of cancer, atherosclerotic plaques, brain function and image-guided therapy.Keywords
Funding Information
- National Basic Research Program of China (2013CB733802, 2014CB744503)
- The National Natural Science Foundation of China (50902093, 81371596, 81371645)
- Intramural Research Program
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