Antidepressant Treatment of Veterans With Parkinson's Disease and Depression: Analysis of a National Sample
- 1 September 2007
- journal article
- research article
- Published by SAGE Publications in Journal of Geriatric Psychiatry and Neurology
- Vol. 20 (3), 161-165
- https://doi.org/10.1177/0891988707301866
Abstract
We examined the impact of comorbid Parkinson's disease (PD) on depression treatment. Using national Veterans Affairs (VA) databases, fiscal year 2002 data were examined for 283 273 elderly males seen for depression. We compared 2 matched depression groups, one with (N = 7868) and one without (N = 7868) PD. In the 12-month period following a depression-related clinic visit, PD and non-PD patients were equally likely to fill an antidepressant prescription (77.8% vs. 77.4%), most commonly for a selective serotonin re-uptake inhibitor (SSRI) (62.9% vs 62.6%). Depressed PD patients had slightly higher rates of newer non-SSRI use (20.6% vs 19.2%, P < .05) and lower rates of tricyclic antidepressant use (7.4% vs 8.9%, P < .001). The presence of a PD diagnosis appears to have little impact on the frequency and type of antidepressant treatment. Efforts to improve the care of depressed PD patients should focus instead on improving recognition, ensuring adequacy of treatment, and evaluating the efficacy of existing antidepressants. ( J Geriatr Psychiatry Neurol 2007;20:161-165)Keywords
This publication has 16 references indexed in Scilit:
- Antidepressant studies in Parkinson's disease: A review and meta‐analysisMovement Disorders, 2005
- Remission in Depressed Geriatric Primary Care Patients: A Report From the PROSPECT StudyAmerican Journal of Psychiatry, 2005
- Effect of Psychiatric and Other Nonmotor Symptoms on Disability in Parkinson's DiseaseJournal of the American Geriatrics Society, 2004
- Evaluation of the Adequacy of Outpatient Antidepressant TreatmentPsychiatric Services, 2003
- Educational and Organizational Interventions to Improve the Management of Depression in Primary CareJAMA, 2003
- A survey of antidepressant drug use in Parkinson's diseaseNeurology, 1997
- Serotonin syndrome and the combined use of deprenyl and an antidepressant in Parkinson's diseaseNeurology, 1997
- The Frequency and Associated Risk Factors for Dementia in Patients With Parkinson's DiseaseArchives of Neurology, 1995
- A prospective longitudinal study of depression, cognitive decline, and physical impairments in patients with Parkinson's disease.Journal of Neurology, Neurosurgery & Psychiatry, 1992
- The relationship of serotonin to depression in Parkinson's diseaseMovement Disorders, 1988