Porcine Endogenous Retrovirus Transmission Characteristics of an Inbred Herd of Miniature Swine
Open Access
- 15 March 2002
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 76 (6), 3045-3048
- https://doi.org/10.1128/jvi.76.6.3045-3048.2002
Abstract
Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences.Keywords
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