Determinants of Small Solute Clearance in Hemodialysis
- 1 January 2005
- journal article
- review article
- Published by Wiley in Seminars in Dialysis
- Vol. 18 (1), 30-35
- https://doi.org/10.1111/j.1525-139x.2005.18101.x
Abstract
Recent outcome trials in chronic dialysis patients raise concerns about the relationship between delivered urea Kt/V and survival. Nevertheless, measurement of delivered small solute clearance remains the most common approach to quantify therapy. The purpose of this review is to provide an overview of the numerous factors influencing small solute clearance during hemodialysis. Although the focus of the review is on the manner in which dialyzer characteristics influence small solute clearances, factors related to other aspects of the extracorporeal circuit and to the patient will also be discussed.Keywords
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