MicroRNA in lung cancer
Open Access
- 11 October 2010
- journal article
- review article
- Published by Springer Science and Business Media LLC in British Journal of Cancer
- Vol. 103 (8), 1144-1148
- https://doi.org/10.1038/sj.bjc.6605901
Abstract
MicroRNAs ( miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction. British Journal of Cancer ( 2010) 103, 1144-1148. doi:10.1038/sj.bjc.6605901 www.bjcancer.com Published online 21 September 2010 (C) 2010 Cancer Research UKThis publication has 66 references indexed in Scilit:
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