FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor
- 20 April 2010
- journal article
- Published by Elsevier BV in Developmental Cell
- Vol. 18 (4), 592-604
- https://doi.org/10.1016/j.devcel.2010.03.008
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related PathologiesScience, 2010
- KSR2 Is an Essential Regulator of AMP Kinase, Energy Expenditure, and Insulin SensitivityCell Metabolism, 2009
- Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative ApoptosisCancer Cell, 2008
- p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR SignalingCell, 2008
- AMPK Phosphorylation of Raptor Mediates a Metabolic CheckpointMolecular Cell, 2008
- A Conserved MST-FOXO Signaling Pathway Mediates Oxidative-Stress Responses and Extends Life SpanCell, 2006
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR ComplexScience, 2005
- Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 DeacetylaseScience, 2004
- Control of cell number byDrosophilaFOXO: downstream and feedback regulation of the insulin receptor pathwayGenes & Development, 2003
- mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth MachineryCell, 2002