Human papillomavirus type 16 associated with multifocal transitional cell carcinomas of the bladder in two transplanted patients
- 1 August 1994
- journal article
- case report
- Published by Frontiers Media SA in Transplant International
- Vol. 7 (5), 340-343
- https://doi.org/10.1007/bf00336709
Abstract
This report describes two cases of rapidly progressive, multifocal transitional cell carcinomas of the bladder that developed in two patients after renal and cardiac transplantation, respectively. In both cases human papillomavirus (HPV) type 16 DNA was detected using the polymerase chain reaction DNA amplification method. To our knowledge, this HPV type has not been previously described in multi‐focal bladder transitional cell carcinoma in transplanted patients. Our findings suggest that HPV may play a major role in the development of rapidly progressive, multifocal transitional cell carcinoma in immunosuppressed patients.Keywords
This publication has 14 references indexed in Scilit:
- High frequency of human papillomavirus infection in carcinoma of the urinary bladderCancer, 1992
- Low incidence of human papillomavirus type 16 DNA in bladder tumor detected by the polymerase chain reactionCancer, 1992
- Detection of Human Papillomavirus DNA in Cancer of the Urinary Bladder by in situ HybridisationBritish Journal of Urology, 1991
- De Novo Carcinoma of the Lower Urinary Tract in Renal Allograft RecipientsJournal of Urology, 1990
- Papillomaviruses and human cancerHuman Pathology, 1990
- Human papillomavirus infectionJournal of the American Academy of Dermatology, 1990
- PAPILLOMAVIRUS INFECTION AND SKIN CANCER IN RENAL ALLOGRAFT RECIPIENTSThe Lancet, 1989
- Human papillomavirus infection and cervical intraepithelial neoplasia in women with renal allografts.BMJ, 1989
- Detection of human papillomavirus-6 in primary carcinoma of the urethra in menCancer, 1987
- Chemoprevention of bladder cancerCancer, 1987