Molecular signatures database (MSigDB) 3.0
Top Cited Papers
- 5 May 2011
- journal article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 27 (12), 1739-1740
- https://doi.org/10.1093/bioinformatics/btr260
Abstract
Motivation: Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale genomic data. The Molecular Signatures Database (MSigDB) is one of the most widely used repositories of such sets. Results: We report the availability of a new version of the database, MSigDB 3.0, with over 6700 gene sets, a complete revision of the collection of canonical pathways and experimental signatures from publications, enhanced annotations and upgrades to the web site. Availability and Implementation: MSigDB is freely available for non-commercial use at http://www.broadinstitute.org/msigdb. Contact: gsea@broadinstitute.orgKeywords
This publication has 13 references indexed in Scilit:
- CCancer: a bird's eye view on gene lists reported in cancer-related studiesNucleic Acids Research, 2010
- ArrayExpress update--from an archive of functional genomics experiments to the atlas of gene expressionNucleic Acids Research, 2009
- NCBI GEO: archive for high-throughput functional genomic dataNucleic Acids Research, 2009
- Reactome knowledgebase of human biological pathways and processesNucleic Acids Research, 2008
- A library of gene expression signatures to illuminate normal and pathological lymphoid biologyImmunological Reviews, 2006
- TRANSFAC(R) and its module TRANSCompel(R): transcriptional gene regulation in eukaryotesNucleic Acids Research, 2006
- Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profilesProceedings of the National Academy of Sciences of the United States of America, 2005
- PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetesNature Genetics, 2003
- Gene Ontology: tool for the unification of biologyNature Genetics, 2000
- KEGG: Kyoto Encyclopedia of Genes and GenomesNucleic Acids Research, 2000