The special problems of travel during pregnancy have become clinically important as more women are traveling to remote places for business or recreation. Optimal maintenance of fetal and maternal health under these circumstances entails specific considerations for which data, unfortunately, remain incomplete. Nevertheless, questions regarding immunizations, antimalarials, therapy for traveler's diarrhea, and even the risks of high altitude or vigorous exercise for the pregnant woman may be examined clinically. With a few important exceptions, sufficient information is available to ensure relatively safe travel in pregnancy provided precautions are taken and preparations are made.