Bone marrow metastases from glioblastoma multiforme – A case report and review of the literature
- 1 April 2005
- journal article
- case report
- Published by Springer Science and Business Media LLC in Journal of Neuro-Oncology
- Vol. 72 (2), 157-161
- https://doi.org/10.1007/s11060-004-3346-y
Abstract
Clinically detected extra-cranial metastases from glioblastoma multiforme (GBM) are quite rare, with an incidence of <2% reported in the published literature. Among the various reported sites of systemic metastases from GBM, there are few cases of clinically symptomatic bone marrow metastasis. The case of a patient developing systemic dissemination of a GBM is described. A 60-year-old man with GBM who developed back pain, thrombocytopenia and subsequently neurological deficits was found to have extensive bony and bone marrow metastases. Previously reported cases of extra-cranial systemic spread of GBM and attempts made in the literature to explain the possible routes of extra-neural dissemination are reviewed.Keywords
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