Chronology of the Gene

Abstract

Summary: The switching of genes from the silent to the operating condition following a rigorous temporal sequence may be called “chronology of the gene”. The succession of times and its biocybernetic mechanism are peculiar to each species, but the duration of information exhibits wide intraspecific variations between populations, families, and individuals. The highly isochronic behavior of MZ twins is proof of the existence of an individual temporal constitution.Our previous studies have proved that the duration of each information is a property of the corresponding genotype, depending on its potential time of activity (chronon), which depends in its turn on the same genotype's energy of stability (ergon).In terms of molecular genetics, the stability against mutation of each gene, governing its Ergon/Chronon (E/G) system, is a function of three factors:(1) Code degeneracy, i.e., the different stability of synonyms coding for the same information through different ratios of GC and AT bases, the former being the more stable.