PKC Regulates a Farnesyl-Electrostatic Switch on K-Ras that Promotes its Association with Bcl-Xl on Mitochondria and Induces Apoptosis
- 17 February 2006
- journal article
- Published by Elsevier BV in Molecular Cell
- Vol. 21 (4), 481-493
- https://doi.org/10.1016/j.molcel.2006.01.012
Abstract
No abstract availableThis publication has 41 references indexed in Scilit:
- Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca2+/calmodulinThe Journal of cell biology, 2005
- PostprenylationCAAXProcessing Is Required for Proper Localization of Ras but Not Rho GTPasesMolecular Biology of the Cell, 2005
- RASSF2 Is a Novel K-Ras-specific Effector and Potential Tumor SuppressorOnline Journal of Public Health Informatics, 2003
- The Pro-apoptotic Ras Effector Nore1 May Serve as a Ras-regulated Tumor Suppressor in the LungOnline Journal of Public Health Informatics, 2003
- BAX and BAK Regulation of Endoplasmic Reticulum Ca 2+ : A Control Point for ApoptosisScience, 2003
- Calmodulin Binds to K-Ras, but Not to H- or N-Ras, and Modulates Its Downstream SignalingMolecular and Cellular Biology, 2001
- Transient Expression of Wild-type or Mitochondrially Targeted Bcl-2 Induces Apoptosis, whereas Transient Expression of Endoplasmic Reticulum-targeted Bcl-2 Is Protective against Bax-induced Cell DeathOnline Journal of Public Health Informatics, 2001
- Bcl-2 differentially targets K-, N-, and H-Ras to mitochondria in IL-2 supplemented or deprived cells: Implications in prevention of apoptosisOncogene, 1999
- The cAMP-dependent protein kinase phosphorylates the rap1 protein in vitro as well as in intact fibroblasts, but not the closely related rap2 proteinBiochemical and Biophysical Research Communications, 1991
- Protein kinase C is required for responses to T cell receptor ligands but not to interleukin-2 in T cellsCell, 1988