Setting the stage: from prodrome to treatment resistance in bipolar disorder
- 2 November 2007
- journal article
- review article
- Published by Wiley in Bipolar Disorders
- Vol. 9 (7), 671-678
- https://doi.org/10.1111/j.1399-5618.2007.00484.x
Abstract
Bipolar disorder is common, and both difficult to detect and diagnose. Treatment is contingent on clinical needs, which differ according to phase and stage of the illness. A staging model could allow examination of the longitudinal course of the illness and the temporal impact of interventions and events. It could allow for a structured examination of the illness, which could set the stage for algorithms that are tailored to the individuals needs. A staging model could further provide as structure for assessment, gauging treatment and outcomes. The model incorporates prodromal stages and emphasizes early detection and algorithm appropriate intervention where possible. At the other end of the spectrum, the model attempts to operationalize treatment resistance. The utility of the model will need to be validated by empirical research.Keywords
This publication has 70 references indexed in Scilit:
- Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective InterventionsAustralian & New Zealand Journal of Psychiatry, 2006
- Relapse prevention in bipolar disorder: a critical review of current guidelinesJournal of Psychopharmacology, 2006
- Bipolar Disorder and Health-Related Quality of LifePharmacoEconomics, 2005
- Phenomenology of Rapid-Cycling Bipolar Disorder: Data From the First 500 Participants in the Systematic Treatment Enhancement ProgramAmerican Journal of Psychiatry, 2004
- Quality of life in patients with bipolar I depression: data from 920 patientsBipolar Disorders, 2004
- Scale matters: the need for a Bipolar Depression Rating Scale (BDRS)Acta Psychiatrica Scandinavica, 2004
- Recent developments in the treatment of bipolar disordersExpert Opinion on Investigational Drugs, 2003
- Recent developments in the treatment of bipolar disordersExpert Opinion on Investigational Drugs, 2003
- Life events and bipolar disorder: Implications from biological theories.Psychological Bulletin, 1995
- Life events and bipolar disorder: Implications from biological theories.Psychological Bulletin, 1995