Cellular mechanisms of nonspecific immunity to intracellular infection: Cytokine-induced synthesis of toxic nitrogen oxides from l-arginine by macrophages and hepatocytes
Open Access
- 31 August 1990
- journal article
- Published by Elsevier BV in Immunology Letters
- Vol. 25 (1-3), 15-19
- https://doi.org/10.1016/0165-2478(90)90083-3
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism.The Journal of Immunology, 1990
- Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages.JCI Insight, 1990
- Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells.The Journal of Experimental Medicine, 1989
- Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.The Journal of Experimental Medicine, 1989
- Nitric oxide: A cytotoxic activated macrophage effector moleculeBiochemical and Biophysical Research Communications, 1988
- Interferon‐γ and tumor necrosis factor induce the L‐arginine‐dependent cytotoxic effector mechanism in murine macrophages*European Journal of Immunology, 1988
- Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells.The Journal of Immunology, 1988
- Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to NitriteScience, 1987
- Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible.JCI Insight, 1986
- Inhibition of Development of Exoerythrocytic Forms of Malaria Parasites by γ-InterferonScience, 1986