Effects of Exercise on Cardiovascular Risk Factors in Type 2 Diabetes
Open Access
- 20 April 2011
- journal article
- research article
- Published by American Diabetes Association in Diabetes Care
- Vol. 34 (5), 1228-1237
- https://doi.org/10.2337/dc10-1881
Abstract
OBJECTIVE Exercise is a cornerstone of diabetes management and the prevention of incident diabetes. However, the impact of the mode of exercise on cardiovascular (CV) risk factors in type 2 diabetes is unclear. RESEARCH DESIGN AND METHODS We conducted a systematic review of the literature between 1970 and October 2009 in representative databases for the effect of aerobic or resistance exercise training on clinical markers of CV risk, including glycemic control, dyslipidemia, blood pressure, and body composition in patients with type 2 diabetes. RESULTS Of 645 articles retrieved, 34 met our inclusion criteria; most investigated aerobic exercise alone, and 10 reported combined exercise training. Aerobic alone or combined with resistance training (RT) significantly improved HbA1c −0.6 and −0.67%, respectively (95% CI −0.98 to −0.27 and −0.93 to −0.40, respectively), systolic blood pressure (SBP) −6.08 and −3.59 mmHg, respectively (95% CI −10.79 to −1.36 and −6.93 to −0.24, respectively), and triglycerides −0.3 mmol/L (95% CI −0.48 to −0.11 and −0.57 to −0.02, respectively). Waist circumference was significantly improved −3.1 cm (95% CI −10.3 to −1.2) with combined aerobic and resistance exercise, although fewer studies and more heterogeneity of the responses were observed in the latter two markers. Resistance exercise alone or combined with any other form of exercise was not found to have any significant effect on CV markers. CONCLUSIONS Aerobic exercise alone or combined with RT improves glycemic control, SBP, triglycerides, and waist circumference. The impact of resistance exercise alone on CV risk markers in type 2 diabetes remains unclear.Keywords
This publication has 31 references indexed in Scilit:
- Management of cardiovascular disease in patients with diabetes: the 2008 Canadian Diabetes Association guidelinesCMAJ : Canadian Medical Association Journal, 2008
- Influence of combined exercise training on indices of obesity, diabetes and cardiovascular risk in type 2 diabetes patientsClinical Rehabilitation, 2008
- Effects of Different Modes of Exercise Training on Glucose Control and Risk Factors for Complications in Type 2 Diabetic PatientsDiabetes Care, 2006
- Exercise for type 2 diabetes mellitusCochrane Database of Systematic Reviews, 2006
- Prevalence of obesity in type 2 diabetes in secondary care: association with cardiovascular risk factorsPublished by Oxford University Press (OUP) ,2006
- Energy Cost of Moderate-Duration Resistance and Aerobic ExerciseJournal of Strength & Conditioning Research, 2005
- Systolic vs diastolic blood pressure and the burden of hypertensionJournal of Human Hypertension, 2002
- Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)The Lancet, 1998
- Diabetes mellitus and risk of idiopathic dilated cardiomyopathy the Washington, DC dilated cardiomyopathy studyAnnals of Epidemiology, 1994
- The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: Contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosisJournal of the American College of Cardiology, 1989