Health-related quality of life in intensively treated young patients with type 1 diabetes
- 28 August 2009
- journal article
- Published by Hindawi Limited in Pediatric Diabetes
- Vol. 10 (6), 374-381
- https://doi.org/10.1111/j.1399-5448.2008.00496.x
Abstract
This study aimed to analyse the impact of the disease and treatment on health‐related quality of life (HRQOL) in intensively treated young patients with diabetes. Our main hypothesis was that metabolic control, gender, age and socio‐economic status predict HRQOL. All children and adolescents (n = 400, 191 girls) and parents in a geographic population of two paediatric clinics in Sweden [mean age 13.2 yr, ±SD 3.9, range 2.6–19.6; mean duration of diabetes 5.1 yr, ±SD 3.8, range 0.3–17.6; yr mean haemoglobin A1c (HbA1c) 7.1%, ±SD 1.2, range 4.0–10.7] received the DISABKIDS questionnaire, a validated combined chronic generic and condition‐specific HRQOL measure for children, and the EuroQol‐5D questionnaire. Parents as proxy perceived HRQOL lower than their children. Adolescents with separated parents reported lower generic HRQOL (GeHRQOL) and diabetes‐specific HRQOL (DiHRQOL) than those with parents living together (p = 0.027 and p = 0.043, respectively). Adolescent girls reported lower GeHRQOL (p = 0.041) and DiHRQOL (p = 0.001) than boys did. Parents of girls <8 yr of age reported lower DiHRQOL (p = 0.047) than did parents of boys <8 yr. In addition, a difference was found in HRQOL between centres. Intensive insulin therapy did not seem to lower HRQOL. If anything, along with better metabolic control, it increased HRQOL. A correlation between DiHRQOL and HbA1c was found in adolescents (r = −0.16, p = 0.046) and boys aged 8–12 yr (r = −0.28, p = 0.045). We conclude that the diabetes team can influence the HRQOL of the patients as there was a centre difference and because HRQOL is influenced by glycaemic control and insulin regimen. Girls seem to need extra support.Keywords
This publication has 35 references indexed in Scilit:
- Monitoring health related quality of life in adolescents with diabetes: a review of measuresArchives of Disease in Childhood, 2007
- How young can children reliably and validly self-report their health-related quality of life?: An analysis of 8,591 children across age subgroups with the PedsQL™ 4.0 Generic Core ScalesHealth and Quality of Life Outcomes, 2007
- Parent proxy-report of their children's health-related quality of life: an analysis of 13,878 parents' reliability and validity across age subgroups using the PedsQL™ 4.0 Generic Core ScalesHealth and Quality of Life Outcomes, 2007
- The European DISABKIDS project: development of seven condition-specific modules to measure health related quality of life in children and adolescentsHealth and Quality of Life Outcomes, 2005
- Care of Children and Adolescents With Type 1 DiabetesDiabetes Care, 2005
- The measurement of health-related quality of life (QOL) in paediatric clinical trials: a systematic reviewHealth and Quality of Life Outcomes, 2004
- The impact of diabetes on health-related quality of life in children and adolescentsPediatric Diabetes, 2003
- Assessing quality of life of children with chronic health conditions and disabilities: a European approachInternational Journal of Rehabilitation Research, 2002
- Children's quality of life measuresArchives of Disease in Childhood, 1997
- The World Health Organization quality of life assessment (WHOQOL): Position paper from the World Health OrganizationSocial Science & Medicine, 1995