Cascade Reactions in Total Synthesis
Top Cited Papers
- 30 October 2006
- journal article
- review article
- Published by Wiley in Angewandte Chemie-International Edition
- Vol. 45 (43), 7134-7186
- https://doi.org/10.1002/anie.200601872
Abstract
The design and implementation of cascade reactions is a challenging facet of organic chemistry, yet one that can impart striking novelty, elegance, and efficiency to synthetic strategies. The application of cascade reactions to natural products synthesis represents a particularly demanding task, but the results can be both stunning and instructive. This Review highlights selected examples of cascade reactions in total synthesis, with particular emphasis on recent applications therein. The examples discussed herein illustrate the power of these processes in the construction of complex molecules and underscore their future potential in chemical synthesis.This publication has 777 references indexed in Scilit:
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