EXCESSIVE GROWTH OF THE SYMPATHETIC GANGLIA EVOKED BY A PROTEIN ISOLATED FROM MOUSE SALIVARY GLANDS
- 1 March 1960
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 46 (3), 373-384
- https://doi.org/10.1073/pnas.46.3.373
Abstract
The results of in vitro effects of the active fraction isolated from mouse salivary glands on human fetal ganglia and of in vivo experiments on the sympathetic ganglia of newborn, young, and adult mice are reported. Injections resulted in a marked increase of the sympathetic ganglia, varying with age of animal, amount and purity of the fraction. Evidence is presented for the presence of the nerve-growth factor in the serum of adult and weanling mice; maximal effects being obtained from adult male mice serum.This publication has 6 references indexed in Scilit:
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