Rapid methods for concurrent measurement of the RF‐pulse flip angle and the longitudinal relaxation time
Open Access
- 6 March 2009
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 61 (6), 1319-1325
- https://doi.org/10.1002/mrm.21900
Abstract
Measuring both the flip angle (FA) and the longitudinal relaxation time T1 is essential in quantitative and longitudinal studies because the signal amplitude is dependent on these quantities. Conventional methods can only measure one of them at a time and require long scan times. In this work, two mutually consistent methods are developed; each can acquire multislice data for determining both the FA and T1 in a scan time about half the time needed for a conventional FA measurement. On the basis of a recent development of longitudinal-relaxation measurement (Hsu and Lowe, J Magn Reson 2004;169:270–278; Hsu and Glover, J Magn Reson 2006;181:98–106), one of the methods uses RF pulse trains of two FAs whereas the other uses pulse trains of different pulse spacing. When only the FA or T1 is needed, the present methods can still be faster than conventional methods for the needed quantity. In benchmarking with a uniform-density sample, both methods generate precise T1 values independent of the FA chosen (except at and near 90°). In the demonstration with three normal volunteers at 3 T, the T1 values of frontal and occipital white matter, putamen, and caudate are compared; the T1 values are in agreement with literature values and the intrasubject deviation is 0.2%–2.8%. Magn Reson Med, 61:1319–1325, 2009.This publication has 20 references indexed in Scilit:
- Magnetic field and tissue dependencies of human brain longitudinal 1H2O relaxation in vivoMagnetic Resonance in Medicine, 2007
- Noninvasive Oxygen Partial Pressure Measurement of Human Body Fluids In Vivo Using Magnetic Resonance ImagingAcademic Radiology, 2006
- Rapid MRI method for mapping the longitudinal relaxation timeJournal of Magnetic Resonance, 2006
- Routine clinical brain MRI sequences for use at 3.0 TeslaJournal of Magnetic Resonance Imaging, 2005
- Measurement and correction of transmitter and receiver induced nonuniformities in vivoMagnetic Resonance in Medicine, 2005
- Spin-lattice relaxation and a fast T1-map acquisition method in MRI with transient-state magnetizationJournal of Magnetic Resonance, 2004
- Imaging of the active B1 field in vivoMagnetic Resonance in Medicine, 1996
- Radiofrequency map of an NMR coil by imagingMagnetic Resonance Imaging, 1993
- Magnetic field mappingMagnetic Resonance in Medicine, 1988
- Comparison of linear and circular polarization for magnetic resonance imagingJournal of Magnetic Resonance (1969), 1985