Diagnostic Approach in Patients with Symmetric Imaging Lesions of the Deep Gray Nuclei
- 1 September 2003
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in The Neurologist
- Vol. 9 (5), 250-261
- https://doi.org/10.1097/01.nrl.0000087718.55597.6a
Abstract
Selective insult to brain deep gray matter nuclei is uncommon, may be congenital or acquired, acute or chronic, and varied in etiology. Determining the etiology relies on history, clinical presentation, laboratory investigations, and lesion pattern on neuroimaging. We review the differential diagnosis and clinical, laboratory and neuroimaging pattern of conditions that manifest with lesions of deep gray matter nuclei in the context of representative case studies. While presentations may vary in individual patients, the essentials of history, clinical examination, laboratory evaluation, and neuroimaging lesion pattern can be efficiently directed to differentiate the various etiologies of deep gray matter nuclei lesions. In this review we focus on the etiologic classification and diagnostic approach to acute and chronic conditions that manifest on neuroimaging with bilateral symmetric lesions of deep gray matter nuclei.Keywords
This publication has 46 references indexed in Scilit:
- Diffusion-weighted MR in hypoglycemic comaNeurology, 2001
- Toxic LeukoencephalopathyNew England Journal of Medicine, 2001
- Bilateral symmetrical basal ganglia infarction after intravenous use of cocaine and heroinClinical Imaging, 2001
- Hyperintense basal ganglia on T1-weighted MR imaging.American Journal of Roentgenology, 1999
- ACUTE LEUKOENCEPHALOPATHIESThe Neurologist, 1998
- Retinocochleocerebral VasculopathyMedicine, 1998
- Magnetic resonance angiography in the diagnosis of deep cerebral venous thrombosisJournal Of Stroke & Cerebrovascular Diseases, 1995
- Mycoplasma pneumoniae infection may cause striatal lesions leading to acute neurologic dysfunctionNeurology, 1993
- Significance of Basal Ganglia Calcification on Computed Tomography in ChildrenPediatric Neurosurgery, 1988
- Changes in the Basal Ganglia Following Cyanide PoisoningJournal of Computer Assisted Tomography, 1981