European evidence-based guidelines on pancreatic cystic neoplasms
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Open Access
- 24 March 2018
- Vol. 67 (5), 789-804
- https://doi.org/10.1136/gutjnl-2018-316027
Abstract
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. This guideline is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club, European-African Hepato-Pancreato-Biliary Association, European Digestive Surgery, and the European Society of Gastrointestinal Endoscopy. It replaces the 2013 European consensus statement guidelines on PCN. European and non-European experts performed systematic reviews and used GRADE methodology to answer relevant clinical questions on nine topics (biomarkers, radiology, endoscopy, intraductal papillary mucinous neoplasm (IPMN), mucinous cystic neoplasm (MCN), serous cystic neoplasm, rare cysts, (neo)adjuvant treatment, and pathology). Recommendations include conservative management, relative and absolute indications for surgery. A conservative approach is recommended for asymptomatic MCN and IPMN measuring 5 mm, and MPD diameter >10 mm. Lifelong follow-up of IPMN is recommended in patients who are fit for surgery. The European evidence-based guidelines on PCN aim to improve the diagnosis and management of PCN.Keywords
This publication has 254 references indexed in Scilit:
- International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancerGut, 2012
- Interobserver agreement in contrast harmonic endoscopic ultrasoundJournal of Gastroenterology and Hepatology, 2012
- Clinicopathological Characteristics and Molecular Analyses of Multifocal Intraductal Papillary Mucinous Neoplasms of the PancreasAnnals of Surgery, 2012
- Outcome of the pancreatic remnant following segmental pancreatectomy for non-invasive intraductal papillary mucinous neoplasmHPB, 2011
- Invasive intraductal papillary mucinous neoplasm: predictors of survival and role of adjuvant therapyHPB, 2010
- Invasive intraductal papillary mucinous neoplasm versus sporadic pancreatic adenocarcinomaCancer, 2010
- Invasive Intraductal Papillary Mucinous Carcinomas of the PancreasAnnals of Surgery, 2010
- Adjuvant Chemoradiotherapy After Pancreatic Resection for Invasive Carcinoma Associated With Intraductal Papillary Mucinous Neoplasm of the PancreasInternational Journal of Radiation Oncology*Biology*Physics, 2010
- Mucin-Producing Neoplasms of the Pancreas: An Analysis of Distinguishing Clinical and Epidemiologic CharacteristicsClinical Gastroenterology and Hepatology, 2010
- Diagnostic evaluation of cystic pancreatic lesionsHPB, 2008