Induction of synthesis of an antimicrobial peptide in the skin of the freeze‐tolerant frog, Rana sylvatica, in response to environmental stimuli
Open Access
- 20 October 2000
- journal article
- Published by Wiley in FEBS Letters
- Vol. 483 (2-3), 135-138
- https://doi.org/10.1016/s0014-5793(00)02102-5
Abstract
An extract of skin taken from specimens of the freeze‐tolerant wood frog, Rana sylvatica, that were collected from cold (Escherichia coli (minimum inhibitory concentration 45 μM) and Staphylococcus aureus (minimum inhibitory concentration 7 μM). The data suggest that synthesis of the peptide is induced when the animal is in an environment that promotes the growth of microorganisms consistent with a role in the animal's defense strategy.Keywords
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