Understanding the Intention-to-treat Principle in Randomized Controlled Trials
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Open Access
- 18 October 2017
- journal article
- review article
- Published by Western Journal of Emergency Medicine in Western Journal of Emergency Medicine
- Vol. 18 (6), 1075-1078
- https://doi.org/10.5811/westjem.2017.8.35985
Abstract
Clinicians, institutions, and policy makers use results from randomized controlled trials to make decisions regarding therapeutic interventions for their patients and populations. Knowing the effect the intervention has on patients in clinical trials is critical for making both individual patient as well as population-based decisions. However, patients in clinical trials do not always adhere to the protocol. Excluding patients from the analysis who violated the research protocol (did not get their intended treatment) can have significant implications that impact the results and analysis of a study.Keywords
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