Mouse gastrulation from a frog's perspective
- 31 August 1995
- journal article
- Published by Elsevier BV in Seminars in Developmental Biology
- Vol. 6 (4), 249-256
- https://doi.org/10.1016/s1044-5781(06)80050-2
Abstract
Although cleaving vertebrate embryos differ profoundly in shape and size, they all rapidly acquire the same characteristic body pattern during gastrulation. Gastrulating mouse and Xenopus embryos share similar fate maps and gene expression patterns. Furthermore, altering the expression of certain genes and transplantation experiments have comparable consequences, indicating that once underway the molecular mechanisms orchestrating gastrulation may be conserved amongst vertebrates. However, it is less clear that vertebrates necessarily share similar strategies for ensuring the localized induction of mesoderm and hence the initiation of gastrulation.Keywords
This publication has 38 references indexed in Scilit:
- Vertebrate Embryonic Induction: Mesodermal and Neural PatterningScience, 1994
- Gastrulation in the mouse embryo: Ultrastructural and molecular aspects of germ layer morphogenesisMicroscopy Research and Technique, 1993
- Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 α, β and γ genes in determination of the definitive endoderm, chordamesoderm and neuroectodermDevelopment, 1993
- The zootype and the phylotypic stageNature, 1993
- Gastrulation in the mouse: The role of the homeobox gene goosecoidCell, 1992
- Analysis of mouse Evx genes: Evx-1 displays graded expression in the primitive streakDevelopmental Biology, 1992
- Expression pattern of the Brachyury gene in whole-mount T WIS/T WIS mutant embryosDevelopment, 1991
- Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryosCell, 1991
- Expression pattern of the mouse T gene and its role in mesoderm formationNature, 1990
- The Presence of Fibroblast Growth Factor in the Frog Egg: Its Role as a Natural Mesoderm InducerScience, 1988