A Prospective Study on Oocyte Survival Rate After ICSI: Influence of Injection Technique and Morphological Features
- 1 January 2001
- journal article
- Published by Springer Science and Business Media LLC in Journal of Assisted Reproduction and Genetics
- Vol. 18 (12), 623-628
- https://doi.org/10.1023/a:1013171505702
Abstract
Purpose: To determine the influence of technical pitfalls and oocyte morphology on survival rate and cleavage behavior after ICSI. Methods: A total of 2210 injection procedures was examined for morphological and technical deviations. Survival rate and cleavage behavior were evaluated. Results: In 77.8% of all cases ICSI was unsuspicous. Out of 491 deviations from optimal injection deep penetration of the oocyte and abundant presence of cumulus cells showed significant correlation with degeneration rate (p < 0.001). Morphological anomalies associated with the periphery of the oocyte were rather related to degeneration than cytoplasmic anomalies (p < 0.001). Early embryonic development was not impaired by technical or morphological parameters. Conclusions: To conclude, these prospective data may be of prognostic value in regard of the number of embryos available for transfer and may help to improve treatment outcome.Keywords
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