The effects of chewing areca/betel quid with and without cigarette smoking on oral submucous fibrosis and oral mucosal lesions
- 1 March 2005
- journal article
- Published by Wiley in Oral Diseases
- Vol. 11 (2), 88-94
- https://doi.org/10.1111/j.1601-0825.2004.01061.x
Abstract
The purpose of this study was to investigate the risk of areca/betel quid chewing with or without cigarette smoking on oral submucous fibrosis (OSF) and other oral mucosal lesions. A stratified case-control study was designed. There were in total 102 patients with oral mucosal lesions or OSF (confirmed pathologically) in the case group. OSF (n = 62) and oral mucosal lesions (n = 62) in 102 subjects were separately analyzed for men and women investigating their risks. For OSF, people with both smoking and chewing habits had a statistically significant odds ratio (OR) 8.68 (95% CI = 1.87, 40.23). For the group of people with chewing habit only and without any lifetime cigarette smoking habit, the OR was 4.51 (95% CI = 1.20, 16.94). For other oral mucosal lesions, people with mixed habits and chewing only had also significant risks (OR = 8.37 and 3.95, respectively). For both OSF and other oral lesions, the ORs of mixed habits and chewing only were both higher in women than in men. The areca/betel quid used in Taiwan does not contain any tobacco product. The only way of areca/betel quid could synergize with any tobacco product is through cigarette smoking. A statistically significant association with oral mucosal lesions and OSF was still found in the group of areca/betel quid chewing only.This publication has 11 references indexed in Scilit:
- The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern TaiwanBritish Journal of Cancer, 2003
- The oral health consequences of chewing areca nutAddiction Biology, 2002
- Epidemiological survey of oral submucous fibrosis and leukoplakia in aborigines of TaiwanJournal of Oral Pathology & Medicine, 2001
- The association between oral leukoplakia and use of tobacco, alcohol and that based on relative risks assessment in KenyaEuropean Journal of Oral Sciences, 1995
- Epidemiology of oral mucosal lesions in United States schoolchildren: 1986‐87Community Dentistry and Oral Epidemiology, 1994
- Role of areca nut in the causation of oral submucous fibrosis: a case‐control study in PakistanJournal of Oral Pathology & Medicine, 1994
- Epidemiological study of oral leukoplakia based on mass screening for oral mucosal diseases in a selected Japanese populationCommunity Dentistry and Oral Epidemiology, 1991
- A case‐control study of oral submucous fibrosis with special reference to the etiologic role of areca nutJournal of Oral Pathology & Medicine, 1990
- THE ESTIMATION AND SIGNIFICANCE OF THE LOGARITHM OF A RATIO OF FREQUENCIESAnnals of Human Genetics, 1956
- ON ESTIMATING THE RELATION BETWEEN BLOOD GROUP AND DISEASEAnnals of Human Genetics, 1955