Efficacy and toxicity of radiation in preparative regimens for pediatric stem cell transplantation. I: Clinical applications and therapeutic effects
- 1 December 1995
- journal article
- review article
- Published by Springer Science and Business Media LLC in Medical Oncology
- Vol. 12 (4), 231-249
- https://doi.org/10.1007/bf02990569
Abstract
Here, we review the role of total body irradiation in the treatment of children with bone marrow transplantation, as well as alternative sources of stem cells. We were unable to demonstrate any clear superiority of TBI-containing preparative regimens, but we were able to find a few definitive reports of significantly enhanced toxicity or important variations in control of the underlying primary diseases, in comparing TBI-based regimens, with those containing only chemotherapy.Keywords
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