Assessment of Infant Brain Development With Frequency-Domain Near-Infrared Spectroscopy
Open Access
- 1 May 2007
- journal article
- research article
- Published by Springer Science and Business Media LLC in Pediatric Research
- Vol. 61 (5, Part 1), 546-551
- https://doi.org/10.1203/pdr.0b013e318045be99
Abstract
This is the first report to demonstrate quantitative monitoring of infant brain development with frequency-domain near-infrared spectroscopy (FD-NIRS). Regionally specific increases in blood volume and oxygen consumption were measured in healthy infants during their first year. The results agree with prior PET and SPECT reports; but, unlike these methods, FD-NIRS is portable and uses nonionizing radiation. Further, new information includes the relatively constant tissue oxygenation with age and location, suggesting a tight control between local oxygen delivery and consumption in healthy infants during brain development. FD-NIRS could become the preferred clinical tool for quantitatively assessing infant brain development.Keywords
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