The effect of a cyclooxygenase inhibitor on thein vivo polymorphonuclear leukocyte migration toPseudomonas aeruginosa peptide chemotactins
- 1 September 1993
- journal article
- inflammation
- Published by Springer Science and Business Media LLC in Inflammation Research
- Vol. 40 (1-2), 106-109
- https://doi.org/10.1007/bf01976758
Abstract
Pseudomonas aeruginosa chemotactic peptides (PAPCs) induced migration of polymorphonuclear leukocytes (PMNL) into the lungs when administered by the aerosol route. Migration of PMNL into the lungs and total protein content of lung lavage fluids in response to PAPCs aerosol challenge, and mortality from lethal challenge withP. aeruginosa were decreased by piroxicam treatment.Keywords
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