Postmastectomy Radiation Therapy and Breast Reconstruction
- 1 May 2010
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Annals of Plastic Surgery
- Vol. 64 (5), 679-683
- https://doi.org/10.1097/sap.0b013e3181db7585
Abstract
The indications for postmastectomy radiotherapy (PMRT) have expanded over the past decade. This study examines PMRT and reconstruction compared with a control group without radiotherapy. There were 919 reconstructed breasts identified (1999-2006) and separated into 3 groups: mastectomy with PMRT before reconstruction (n = 57), immediate reconstruction then PMRT (n = 59), and reconstruction without PMRT (n = 665). A validated questionnaire assessed patient satisfaction (response rate 73.7%). Overall complication rates for patients undergoing PMRT (before and after reconstruction) were higher than that of the controls (39.66% vs. 23.16%, P < 0.001). Immediate reconstruction before PMRT had increased overall and late (>90 days) complication rates, compared with controls (47.46% vs. 23.16%, P < 0.001; 33.90% vs. 15.59%, P < 0.001, respectively); however general and aesthetic satisfaction was similar. In contrast, PMRT before reconstruction has similar complication rates and general satisfaction with controls, but decreased aesthetic satisfaction (50% vs. 66.88%, P < 0.035).Keywords
This publication has 26 references indexed in Scilit:
- Keeping Options Open for Patients with Anticipated Postmastectomy Chest Wall Irradiation: Immediate Tissue Expansion Followed by Reconstruction of ChoicePlastic and Reconstructive Surgery, 2009
- New Trends in Breast Cancer ManagementAnnals of Surgery, 2006
- Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trialsThe Lancet, 2005
- Breast Reconstruction with Postmastectomy Radiation Therapy: Current IssuesPlastic and Reconstructive Surgery, 2004
- Delayed-Immediate Breast ReconstructionPlastic and Reconstructive Surgery, 2004
- Radiation Effects on Breast Reconstruction with the Deep Inferior Epigastric Perforator FlapPlastic and Reconstructive Surgery, 2002
- Comparison of Immediate and Delayed Free TRAM Flap Breast Reconstruction in Patients Receiving Postmastectomy Radiation TherapyPlastic and Reconstructive Surgery, 2001
- Postmastectomy Radiotherapy: Clinical Practice Guidelines of the American Society of Clinical Oncology*Journal of Clinical Oncology, 2001
- Postoperative Adjuvant Irradiation: Effects on Tranverse Rectus Abdominis Muscle Flap Breast ReconstructionPlastic and Reconstructive Surgery, 2000
- Staged Breast Reconstruction with Saline-Filled Implants in the Irradiated Breast: Recent Trends and Therapeutic ImplicationsPlastic & Reconstructive Surgery, 2000