Limitations of Chloride Determination in the Diagnosis of Bromism

Abstract
AN apparently elevated serum chloride level is recognized as a clue to significant bromism, but this phenomenon occurs with only one of two common methods of chloride determination.Case HistoryA 35-year-old man had polyuria, polydipsia, increased anxiety and somnolence that necessitated admission to a hospital. Physical examination and laboratory tests were within normal limits. Psychotic behavior and persistent fever prompted transfer to the Clinical Center for evaluation. A history of ingestion of a preparation containing sodium, potassium and ammonium bromide* was obtained. It was estimated that he had ingested 1060 mEq of bromide during the week before admission. The . . .