Capsular Serotype–Specific Attack Rates and Duration of Carriage ofStreptococcuspneumoniaein a Population of Children

Abstract

BackgroundThe relative invasiveness rates (attack rates) of Streptococcus pneumoniae of different capsular serotypes in children are not known. Estimates of capsular serotype invasiveness (designated “invasive odds ratios”) that are based on cross-sectional prevalence carriage data have been published, but these estimates could be biased by variation in the duration of carriage