Abstract
Helicobacter pylori infection is now widely accepted to be an important risk factor for a number of gastric and duodenal disorders. It is the major aetiological factor for gastric and duodenal ulcers unrelated to NSAID or aspirin-usage. In addition, it plays an essential role in the aetiology of most cases of non-cardia gastric cancer as well as low-grade gastric MALTomas. Such is the importance of H pylori infection in disorders of the stomach and duodenum that pathology distal to the gastro-oesophageal junction is rarely encountered when endoscoping H pylori naive subjects.

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