Antibacterial activity of honey against clinical isolates of Escherichia coli, Pseudomonas aeruginosa and Salmonella enterica serovar Typhi
Open Access
- 31 December 2010
- journal article
- Published by Medknow in Asian Pacific Journal of Tropical Medicine
- Vol. 3 (12), 961-964
- https://doi.org/10.1016/s1995-7645(11)60009-6
Abstract
Objective: To ascertain the potential antibacterial activity of honey against clinical isolates of Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa) and Salmonella enterica serovar Typhi (S. enterica serovar Typhi) by in vitro methods. Methods: The partial inhibitory concentration (PIC), minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of the autoclaved honey (extracted from Apis indica hive by indigenous method) were determined for S. enterica serovar Typhi (n=8; from blood cultute), E. coli (n=5; from urine culture) and P. aeruginosa (n=5; from pus culture) isolates by in vitro methods. Results: The PICs of the honey tested for the isolates ranged 0.50%-1.25 % (v/v) for S. enterica serovar Typhi, 0.75%-1.50% (v/v) for E. coli and 1.00%-1.25 % (v/v) for P. aeruginosa, while the MICs ranged 1.75%–3.00% (v/v), 3.00%-3.50% (v/v) and 3.50% (v/v), respectively. The P. aeruginosa and E. coli isolates had MBC value of 4.00% (v/v); the S. enterica serovar Typhi showed MBCs in between 3.00% and 3.50% (v/v). The bactericidal activity of honey was achieved at concentration 3.00% (v/v) for S. enterica serovar Typhi and E. coli, and at 3.50% (v/v) for P. aeruginosa. Conclusions: The excellent antibacterial activity of honey against clinical bacterial isolates indicates the usefulness of honey in clinical practice against bacterial infection.Keywords
This publication has 19 references indexed in Scilit:
- Synergistic anti–Staphylococcus aureus activity of amoxicillin in combination with Emblica officinalis and Nymphae odorata extractsAsian Pacific Journal of Tropical Medicine, 2010
- Antibacterial properties of tualang honey and its effect in burn wound management: a comparative studyBMC Complementary and Alternative Medicine, 2010
- The antibacterial properties of Malaysian tualang honey against wound and enteric microorganisms in comparison to manuka honeyBMC Complementary and Alternative Medicine, 2009
- Antimicrobial activity of two South African honeys produced from indigenous Leucospermum cordifolium and Erica species on selected micro-organismsBMC Complementary and Alternative Medicine, 2008
- Bactericidal Activity of Different Types of Honey against Clinical and Environmental Isolates ofPseudomonas aeruginosaThe Journal of Alternative and Complementary Medicine, 2007
- The antibacterial activity of honey against coagulase-negative staphylococciJournal of Antimicrobial Chemotherapy, 2005
- Antibacterial Activity of 13 Honeys Against Escherichia coli and Pseudomonas aeruginosaJournal of Medicinal Food, 2005
- Growth inhibition of foodborne pathogens and food spoilage organisms by select raw honeysInternational Journal of Food Microbiology, 2004
- Investigating the Antimicrobial Activity of Natural Honey and Its Effects on the Pathogenic Bacterial Infections of Surgical Wounds and ConjunctivaJournal of Medicinal Food, 2004
- The Efficacy of Honey in Inhibiting Strains of Pseudomonas Aeruginosa From Infected BurnsJournal of Burn Care & Rehabilitation, 2002