This study assessed cancer knowledge, attitudes, beliefs, and practices (KABP) among 1,280 African American and Hispanic women. A written self-report KABP survey was administered. Most women reported using breast self-examination (BSE), clinical breast examination (CBE), and mammography, but only 66% had had Pap tests in the preceding year. Group comparisons revealed significant differences for cancer and disease beliefs between the Black and the Hispanic women. Less knowledge about screening significantly predicted underutilization of Pap testing (OR = 2.71, CI 2.02, 3.63), BSE (OR = 1.63, CI 1.63, 2.13), and CBE (OR = 1.66, CI 1.27, 2.18). KABP surveys were important in developing cancer interventions.