Cancer incidence among copper smelting and nickel refining workers in Finland
- 17 October 2016
- journal article
- research article
- Published by Wiley in American Journal of Industrial Medicine
- Vol. 60 (1), 87-95
- https://doi.org/10.1002/ajim.22662
Abstract
Among workers employed at a nickel refinery in Harjavalta, Finland an increased risk of lung and sinus cancer has been demonstrated in two previous studies. The current study adds 16 more years of follow-up to these studies. A total of 1,115 persons exposed to nickel and 194 non-exposed workers in the Harjavalta nickel smelter and refinery were followed up for cancer from 1967 to 2011 through the Finnish Cancer Registry. The total number of cancer cases in men was 251 (Standardized incidence ratio (SIR) 1.05) and in women 12 (SIR 1.22). In the most nickel-exposed work site (refinery), there were 14 lung cancers (SIR 2.01) and 3 sinonasal cancers (SIR 26.7, 95%). It is likely that exposure to nickel compounds is the main reason for elevated nasal cancer risk among the nickel refinery employees and may also contribute to the excess risk of lung cancer. Am. J. Ind. Med.Keywords
This publication has 22 references indexed in Scilit:
- Cancer incidence among Finnish ferrochromium and stainless steel production workers in 1967–2011: a cohort studyBMJ Open, 2013
- Evidence of carcinogenicity in humans of water-soluble nickel saltsJournal of Occupational Medicine and Toxicology, 2010
- Characterization and Assessment of Dermal and Inhalable Nickel Exposures in Nickel Production and Primary User IndustriesAnnals of Work Exposures and Health, 2009
- Occupation and cancer – follow-up of 15 million people in five Nordic countriesActa Oncologica, 2009
- Mortality study of nickel platers with special reference to cancers of the stomach and lung, 1945-93.Occupational and Environmental Medicine, 1996
- Exposure to nickel compounds and smoking in relation to incidence of lung and nasal cancer among nickel refinery workers.Occupational and Environmental Medicine, 1996
- Pooled reanalysis of cancer mortality among five cohorts of workers in wood-related industriesScandinavian Journal of Work, Environment & Health, 1995
- Exposure to stainless steel welding fumes and lung cancer: a meta-analysis.Occupational and Environmental Medicine, 1994
- Report of the International Committee on Nickel Carcinogenesis in Man.Scandinavian Journal of Work, Environment & Health, 1990