Fluorescence quenching of gold nanoparticles integrating with a conformation-switched hairpin oligonucleotide probe for microRNA detection
- 21 August 2012
- journal article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 48 (87), 10718-10720
- https://doi.org/10.1039/c2cc35564g
Abstract
We report a new strategy for microRNA analysis based on the fluorescence quenching of gold nanoparticles (AuNPs) integrating with a conformation-switched hairpin-structured oligonucleotide probe for improving selectivity.Keywords
This publication has 20 references indexed in Scilit:
- Attomolar Ultrasensitive MicroRNA Detection by DNA-Scaffolded Silver-Nanocluster Probe Based on Isothermal AmplificationAnalytical Chemistry, 2012
- Rapid Detection of MicroRNA by a Silver Nanocluster DNA ProbeAnalytical Chemistry, 2011
- Simultaneous Detection of Intracellular Tumor mRNA with Bi‐Color Imaging Based on a Gold Nanoparticle/Molecular BeaconChemistry – A European Journal, 2011
- Causes and consequences of microRNA dysregulation in cancerNature Reviews Genetics, 2009
- Real-Time Polymerase Chain Reaction MicroRNA Detection Based on Enzymatic Stem-Loop Probes LigationAnalytical Chemistry, 2009
- Expression of islet-specific microRNAs during human pancreatic developmentGene Expression Patterns, 2009
- MicroRNAs: Target Recognition and Regulatory FunctionsCell, 2009
- Carbodiimide-mediated cross-linking of RNA to nylon membranes improves the detection of siRNA, miRNA and piRNA by northern blotNucleic Acids Research, 2007
- Simple, quantitative primer-extension PCR assay for direct monitoring of microRNAs and short-interfering RNAsRNA, 2005
- A custom microarray platform for analysis of microRNA gene expressionNature Methods, 2004