Identification of a new analogue of sildenafil added illegally to a functional food marketed for penile erectile dysfunction
- 1 September 2003
- journal article
- research article
- Published by Informa UK Limited in Food Additives & Contaminants
- Vol. 20 (9), 793-796
- https://doi.org/10.1080/0265203031000121455
Abstract
A new analogue of sildenafil was discovered to have been added illegally to a functional food marketed for penile erectile dysfunction. The structure of the analogue was established by various NMR spectroscopic techniques (including DEPT, COSY, TOCSY, HMQC, HMBC). Because of the addition of a methylene group to sildenafil, the main ingredient of Viagra®, it was given the name homosildenafil, and this has never been reported previously. An analytical method using HPLC was proposed. Homosildenafil was added as a new inspection item and other foods have since been discovered to contain it.Keywords
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