On-line optical imaging of the human brain with 160-ms temporal resolution
Open Access
- 31 January 2000
- journal article
- Published by Optica Publishing Group in Optics Express
- Vol. 6 (3), 49-57
- https://doi.org/10.1364/oe.6.000049
Abstract
We have developed an instrument for non-invasive optical imaging of the human brain that produces on-line images with a temporal resolution of 160 ms. The imaged quantities are the temporal changes in cerebral oxy-hemoglobin and deoxy-hemoglobin concentrations. We report real-time videos of the arterial pulsation and motor activation recorded on a 4×9 cm2 area of the cerebral cortex in a healthy human subject. This approach to optical brain imaging is a powerful tool for the investigation of the spatial and temporal features of the optical signals collected on the brain.Keywords
This publication has 30 references indexed in Scilit:
- Fluctuations in the cerebral oxygenation state during the resting period in functional mapping studies of the human brainMedical & Biological Engineering & Computing, 1997
- Cerebral oxygenation changes in response to motor stimulationJournal of Applied Physiology, 1996
- Spatial and temporal analysis of human motor activity using noninvasive NIR topographyMedical Physics, 1995
- Rapid Changes of Optical Parameters in the Human Brain During a Tapping TaskJournal of Cognitive Neuroscience, 1995
- Dynamic features of hemodynamic and metabolic changes in the human brain during all-night sleep as revealed by near-infrared spectroscopyBrain Research, 1994
- Near-infrared spectroscopic localization of intracranial hematomasJournal of Neurosurgery, 1993
- Near infrared spectroscopy (NIRS): A new tool to study hemodynamic changes during activation of brain function in human adultsNeuroscience Letters, 1993
- Human Visual Cortical Function during Photic Stimulation Monitoring by Means of near-Infrared SpectroscopyJournal of Cerebral Blood Flow & Metabolism, 1993
- Cognition-activated low-frequency modulation of light absorption in human brain.Proceedings of the National Academy of Sciences of the United States of America, 1993
- Detection of dynamic changes in cerebral oxygenation coupled to neuronal function during mental work in manNeuroscience Letters, 1993