Opiate Receptor: Demonstration in Nervous Tissue
- 9 March 1973
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 179 (4077), 1011-1014
- https://doi.org/10.1126/science.179.4077.1011
Abstract
Tritiated naloxone, a powerful opiate antagonist, specifically binds to an opiate receptor of mammalian brain and guinea pig intestine. Competition for the opiate receptor by various opiates and their antagonists closely parallels their pharmacological potency. The opiate receptor is confined to nervous tissue.Keywords
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