Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine
Open Access
- 23 September 2010
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 8 (22), 5053-5055
- https://doi.org/10.1039/c0ob00413h
Abstract
A fluorescent nucleobase analogue, 7-aminoquinazoline-2,4-(1H,3H)-dione, is incorporated into a DNA oligonucleotide and senses mismatched pairing by displaying G-specific fluorescence enhancement.Keywords
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