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Selective Monoalkylation of Ammonia: A High Throughput Synthesis of Primary Amines
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Selective Monoalkylation of Ammonia: A High Throughput Synthesis of Primary Amines
Selective Monoalkylation of Ammonia: A High Throughput Synthesis of Primary Amines
SB
Sukanta Bhattacharyya
Sukanta Bhattacharyya
KN
Kurt A. Neidigh
Kurt A. Neidigh
MA
Mitchell A. Avery
Mitchell A. Avery
John S. Williamson
John S. Williamson
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1 November 1999
journal article
letter
Published by
Georg Thieme Verlag KG
in
Synlett
Vol. 1999
(11)
,
1781-1783
https://doi.org/10.1055/s-1999-2946
Abstract
Primary amines are obtained in good to excellent yields by highly selective monoalkylation of ammonia with alkyl and aryl ketones using titanium(IV) isopropoxide and sodium borohydride.
Keywords
PRIMARY AMINES
REDUCTIVE AMINATION
TITANIUM(IV) ISOPROPOXIDE
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Cited by 30 articles