Sweet's syndrome as the presenting symptom of hairy cell leukemia with concomitant infection by Mycobacterium kansasii
- 1 July 1992
- journal article
- case report
- Published by Springer Science and Business Media LLC in Annals of Hematology
- Vol. 65 (1), 55-58
- https://doi.org/10.1007/bf01715129
Abstract
A patient with Sweet's syndrome and leukopenia is reported. Hematological evaluation revealed hairy cell leukemia (HCL). The clinical picture was dominated by persistent fever, which is a common feature of both Sweet's syndrome and HCL. Since fever frequently reflects concomitant infection in HCL, a thorough search for infectious disease was performed. Blood cultures grewMycobacterium kansasii. The patient recovered after treatment with recombinant interferon-α (r-IFN-α) and tuberculostatic drugs. Remarkably, the skin lesions completely regressed within 1 week after the start of r-IFN-α. In the literature, Sweet's syndrome is rarely mentioned as a feature of HCL. Mycobacterial disease, especially atypical mycobacteria, is relatively often seen in HCL.Keywords
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