Inhibition of microglial activation with minocycline at the intrathecal level attenuates sympathoexcitatory and proarrhythmogenic changes in rats with chronic temporal lobe epilepsy
Open Access
- 1 May 2017
- journal article
- research article
- Published by Elsevier BV in Neuroscience
- Vol. 350, 23-38
- https://doi.org/10.1016/j.neuroscience.2017.03.012
Abstract
No abstract availableKeywords
Funding Information
- Australian Research Council (DE120100992)
- National Health and Medical Research Council of Australia (1024489, 1065485, 1082215, 1082215)
- international Macquarie University Research Excellence Scholarships (2012219, 2012112)
- The Heart Research Institute
- The University of Sydney
This publication has 80 references indexed in Scilit:
- Microglia PACAP and glutamate: Friends or foes in seizure-induced autonomic dysfunction and SUDEP?Respiratory Physiology & Neurobiology, 2016
- Seizure-Induced Sympathoexcitation Is Caused by Activation of Glutamatergic Receptors in RVLM That Also Causes Proarrhythmogenic Changes Mediated by PACAP and Microglia in RatsJournal of Neuroscience, 2016
- Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse modelsEpilepsia, 2015
- Antagonism of PACAP or Microglia Function Worsens the Cardiovascular Consequences of Kainic-Acid-Induced Seizures in RatsJournal of Neuroscience, 2015
- Delayed Pituitary Adenylate Cyclase–Activating Polypeptide Delivery After Brain Stroke Improves Functional Recovery by Inducing M2 Microglia/Macrophage PolarizationStroke, 2015
- Confounding neurodegenerative effects of manganese for in vivo MR imaging in rat models of brain insultsJournal of Magnetic Resonance Imaging, 2011
- Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factorsBrain, 2008
- Effects of epilepsy on autonomic nervous system and respiratory function testsEpilepsy & Behavior, 2004
- Interictal Cardiovascular Autonomic Responses in Patients with Temporal Lobe EpilepsyEpilepsia, 2000
- Reactive microglia in hippocampal sclerosis associated with human temporal lobe epilepsyNeuroscience Letters, 1995