SAR650984 directly induces multiple myeloma cell death via lysosomal-associated and apoptotic pathways, which is further enhanced by pomalidomide
- 4 September 2015
- journal article
- research article
- Published by Springer Science and Business Media LLC in Leukemia
- Vol. 30 (2), 399-408
- https://doi.org/10.1038/leu.2015.240
Abstract
No abstract availableThis publication has 45 references indexed in Scilit:
- Combating apoptosis and multidrug resistant cancers by targeting lysosomesCancer Letters, 2013
- Long-Term Analysis of the IFM 99 Trials for Myeloma: Cytogenetic Abnormalities [t(4;14), del(17p), 1q gains] Play a Major Role in Defining Long-Term SurvivalJournal of Clinical Oncology, 2012
- Trisomies in multiple myeloma: impact on survival in patients with high-risk cytogeneticsBlood, 2012
- Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignanciesBlood, 2011
- Evidence for Cytogenetic and Fluorescence In Situ Hybridization Risk Stratification of Newly Diagnosed Multiple Myeloma in the Era of Novel TherapiesMayo Clinic Proceedings, 2010
- Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathologyNature, 2010
- Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cellsJCI Insight, 2009
- Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeletonHaematologica, 2009
- Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieuBlood, 2008
- Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammationThe Journal of Experimental Medicine, 2008