Prognostic Impact of Nutritional Status in Asymptomatic Patients With Cardiac Diseases
Open Access
- 1 January 2013
- journal article
- clinical trial
- Published by Japanese Circulation Society in Circulation Journal
- Vol. 77 (9), 2318-2326
- https://doi.org/10.1253/circj.cj-13-0127
Abstract
Background: The prognostic impact of nutritional status is poorly understood in asymptomatic patients with structural and/or functional heart diseases, classified as stage B in the ESC/AHA/ACC chronic heart failure (HF) guidelines. Methods and Results: We evaluated the impact of nutrition, using the controlling nutritional status (CONUT) score, calculated by the serum albumin and total cholesterol levels,and lymphocyte number, in 3,421 stage B patients from the Chronic Heart Failure Analysis and Registry in the Tohoku District-2 Study (mean age: 66.9±12.7 years, male: 71.6%). During a median follow-up of 2.89 years, 224 patients died from cardiovascular (45%, n=102) and noncardiovascular (55%, n=123) causes and 139 experienced hospitalization for HF. Survival at 3 years in patients with CONUT 0–1 (reference, n=2,121), 2 (n=693) and ≥3 (n=607) was 95.5, 92.3, and 73.2%, respectively (PConclusions: In the current stage B patients, poor nutritional status was associated with increased incidence of death for the overall population and of HF hospitalization for the elderly proportion. (Circ J 2013; 77: 2318–2326)Keywords
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