Aging and Cancer: Converging Routes to Disease Prevention
Open Access
- 1 June 2009
- journal article
- review article
- Published by SAGE Publications in Integrative Cancer Therapies
- Vol. 8 (2), 115-122
- https://doi.org/10.1177/1534735409335505
Abstract
An integrative approach to the combined challenges of aging, cancer and stress is a necessary part of a global vision of wellness. Recent research into the mechanisms of aging, cancer and stress has established the biological links between these processes. Understanding these links is an important stepping-stone for developing approaches and therapies that ensure wellness throughout all stages of aging. This paper will consider the most recent developments in research into the molecular mechanisms common to aging and cancer and will discuss the effectiveness of natural approaches for preventing disease. Metabolic regulators as well as nutrient and energy sensors are involved in the processes of aging and cancer, and these are open to external manipulation and control. It is now becoming possible to demonstrate how nutrition, physical activity and stress control can lead to disease-free aging.Keywords
This publication has 83 references indexed in Scilit:
- Reactive oxygen species: Destroyers or messengers?Biochemical Pharmacology, 2009
- Hypoxic Reactive Oxygen Species Regulate the Integrated Stress Response and Cell SurvivalPublished by Elsevier BV ,2008
- Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidationNeurobiology of Learning and Memory, 2008
- Multitargeted therapy of cancer by green tea polyphenolsCancer Letters, 2008
- Mechanisms Underlying Caloric Restriction and Lifespan RegulationCirculation Research, 2008
- DNA-damage repair; the good, the bad, and the uglyThe EMBO Journal, 2008
- ROS and p53: A versatile partnershipFree Radical Biology & Medicine, 2008
- Profiling influences of senescent and aged fibroblasts on prostate carcinogenesisBritish Journal of Cancer, 2008
- Free radicals and antioxidants in normal physiological functions and human diseaseThe International Journal of Biochemistry & Cell Biology, 2007
- Caloric restriction and genomic stabilityNucleic Acids Research, 2007